One interface. Any biological model.

Biosimulant is an open source framework for humans and agents to build, compose and run any biomodel, from Boltz, DiffDock, and SBML pathways to your own custom dynamics.

Completed runBoltz: Boltz2AffinityPredictor Labsnapshot 4dc05694Open the lab (opens in a new tab)
Predicted protein-ligand complex from the Boltz-2 affinity lab: the protein drawn as a ribbon with the ligand bound in its pocket.predicted_structure · mmCIF

Confidence outputs

Confidence
0.921
pTM
0.933
ipTM
0.906
Complex pLDDT
0.924

Ports and profiles

  • inprotein_sequenceprotein.sequence/v1
  • inligand_smileschemical.smiles/v1
  • outpredicted_structureprotein-ligand.complex-structure-mmcif/v1
  • outbinding_probabilityboltz.binding-probability/v1

Biology has the models. It's missing the framework.

There are decades of SBML pathways, CellML cells and NeuroML neurons, and AI models like Boltz-2 and DiffDock are arriving too. Getting any two of them to run together still means writing custom code for that one connection, so only specialists do it, and every team throws the glue away when the project ends.

Our goal is to simulate biology. All of it, eventually, which isn't something any one company can do. We're building the shared, open layer that lets anyone compose, run and share biology simulations as easily as writing code. Do the work once, in the open, and the results start adding up.

Biotech, beyond the specialists

A real framework turns biology into a developer tool. If you can write Python, you can compose and run models, so far more people can build.

Built for the agent era

As coding agents take over more of the code layer, they need one consistent interface to build against. A shared contract across every standard lets agents compose and run biomodels they've never seen, without learning each format's quirks.

Biosimulant, in five quick answers.

Understand the idea, see what a run produces, and choose how you want to start.

A biology model is a runnable description of part of a living system, from a cell growing to a protein binding. It helps scientists test ideas and compare outcomes in systems that are difficult to study directly.